Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort
Identifieur interne : 005D51 ( Main/Exploration ); précédent : 005D50; suivant : 005D52Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort
Auteurs : Peter J. Campbell [Royaume-Uni] ; Cathy Maclean [Royaume-Uni] ; Philip A. Beer [Royaume-Uni] ; Georgina Buck [Royaume-Uni] ; Keith Wheatley [Royaume-Uni] ; Jean-Jacques Kiladjian [France] ; Cecily Forsyth [Australie] ; Claire N. Harrison [Royaume-Uni] ; Anthony R. Green [Royaume-Uni]Source :
- Blood [ 0006-4971 ] ; 2012.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Prospective.
English descriptors
- KwdEn :
Abstract
Essential thrombocythemia, a myeloproliferative neoplasm, is associated with increased platelet count and risk of thrombosis or hemorrhage. Cytoreductive therapy aims to normalize platelet counts despite there being only a minimal association between platelet count and complication rates. Evidence is increasing for a correlation between WBC count and thrombosis, but prospective data are lacking. In the present study, we investigated the relationship between vascular complications and 21 887 longitudinal blood counts in a prospective, multicenter cohort of 776 essential thrombocythemia patients. After correction for confounding variables, no association was seen between blood counts at diagnosis and future complications. However, platelet count outside of the normal range during follow-up was associated with an immediate risk of major hemorrhage (P = .0005) but not thrombosis (P = .7). Elevated WBC count during follow-up was correlated with thrombosis (P = .05) and major hemorrhage (P=.01). These data imply that the aim of cytoreduction in essential thrombocythemia should be to keep the platelet count, and arguably the WBC count, within the normal range. This study is registered at the International Standard Randomized Controlled Trials Number Registry (www.isrctn.org) as number 72251782.
Url:
Affiliations:
- Australie, France, Royaume-Uni
- Angleterre, Angleterre de l'Est, Grand Londres, Midlands de l'Ouest, Oxfordshire, Île-de-France
- Birmingham, Cambridge, Londres, Oxford, Paris
- Université d'Oxford, Université de Birmingham, Université de Cambridge
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 001076
- to stream PascalFrancis, to step Curation: 004E41
- to stream PascalFrancis, to step Checkpoint: 001231
- to stream Main, to step Merge: 006066
- to stream Pmc, to step Corpus: 001228
- to stream Pmc, to step Curation: 001089
- to stream Pmc, to step Checkpoint: 001F91
- to stream Ncbi, to step Merge: 000E65
- to stream Ncbi, to step Curation: 000E65
- to stream Ncbi, to step Checkpoint: 000E65
- to stream Main, to step Merge: 005668
- to stream Main, to step Curation: 005D51
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort</title><author><name sortKey="Campbell, Peter J" sort="Campbell, Peter J" uniqKey="Campbell P" first="Peter J." last="Campbell">Peter J. Campbell</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Cancer Genome Project, Wellcome Trust Sanger Institute</s1><s2>Hinxton</s2><s3>GBR</s3><sZ>1 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Hinxton</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author><author><name sortKey="Maclean, Cathy" sort="Maclean, Cathy" uniqKey="Maclean C" first="Cathy" last="Maclean">Cathy Maclean</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Haematology, Addenbrooke's Hospital</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author><author><name sortKey="Beer, Philip A" sort="Beer, Philip A" uniqKey="Beer P" first="Philip A." last="Beer">Philip A. Beer</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Haematology, Addenbrooke's Hospital</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author><author><name sortKey="Buck, Georgina" sort="Buck, Georgina" uniqKey="Buck G" first="Georgina" last="Buck">Georgina Buck</name><affiliation wicri:level="4"><inist:fA14 i1="04"><s1>Clinical Trial Service Unit, University of Oxford</s1><s2>Oxford</s2><s3>GBR</s3><sZ>4 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Wheatley, Keith" sort="Wheatley, Keith" uniqKey="Wheatley K" first="Keith" last="Wheatley">Keith Wheatley</name><affiliation wicri:level="4"><inist:fA14 i1="05"><s1>Cancer Research UK Clinical Trials Unit, University of Birmingham</s1><s2>Birmingham</s2><s3>GBR</s3><sZ>5 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region><settlement type="city">Birmingham</settlement></placeName><orgName type="university">Université de Birmingham</orgName></affiliation></author><author><name sortKey="Kiladjian, Jean Jacques" sort="Kiladjian, Jean Jacques" uniqKey="Kiladjian J" first="Jean-Jacques" last="Kiladjian">Jean-Jacques Kiladjian</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Assistance Publique des Hôpitaux de Paris Hopital Saint-Louis, Centre d'Investigations Cliniques</s1><s2>Paris</s2><s3>FRA</s3><sZ>6 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Forsyth, Cecily" sort="Forsyth, Cecily" uniqKey="Forsyth C" first="Cecily" last="Forsyth">Cecily Forsyth</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Gosford Hospital</s1><s2>Gosford</s2><s3>AUS</s3><sZ>7 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Gosford Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Harrison, Claire N" sort="Harrison, Claire N" uniqKey="Harrison C" first="Claire N." last="Harrison">Claire N. Harrison</name><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>St Thomas's Hospital</s1><s2>London</s2><s3>GBR</s3><sZ>8 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Green, Anthony R" sort="Green, Anthony R" uniqKey="Green A" first="Anthony R." last="Green">Anthony R. Green</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Haematology, Addenbrooke's Hospital</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0349846</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0349846 INIST</idno><idno type="RBID">Pascal:12-0349846</idno><idno type="wicri:Area/PascalFrancis/Corpus">001076</idno><idno type="wicri:Area/PascalFrancis/Curation">004E41</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001231</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">001231</idno><idno type="wicri:doubleKey">0006-4971:2012:Campbell P:correlation:of:blood</idno><idno type="wicri:Area/Main/Merge">006066</idno><idno type="wicri:source">PMC</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470936</idno><idno type="RBID">PMC:3470936</idno><idno type="wicri:Area/Pmc/Corpus">001228</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001228</idno><idno type="wicri:Area/Pmc/Curation">001089</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001089</idno><idno type="wicri:Area/Pmc/Checkpoint">001F91</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001F91</idno><idno type="wicri:Area/Ncbi/Merge">000E65</idno><idno type="wicri:Area/Ncbi/Curation">000E65</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E65</idno><idno type="wicri:doubleKey">0006-4971:2012:Campbell P:correlation:of:blood</idno><idno type="wicri:Area/Main/Merge">005668</idno><idno type="wicri:Area/Main/Curation">005D51</idno><idno type="wicri:Area/Main/Exploration">005D51</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort</title><author><name sortKey="Campbell, Peter J" sort="Campbell, Peter J" uniqKey="Campbell P" first="Peter J." last="Campbell">Peter J. Campbell</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Cancer Genome Project, Wellcome Trust Sanger Institute</s1><s2>Hinxton</s2><s3>GBR</s3><sZ>1 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Hinxton</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author><author><name sortKey="Maclean, Cathy" sort="Maclean, Cathy" uniqKey="Maclean C" first="Cathy" last="Maclean">Cathy Maclean</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Haematology, Addenbrooke's Hospital</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author><author><name sortKey="Beer, Philip A" sort="Beer, Philip A" uniqKey="Beer P" first="Philip A." last="Beer">Philip A. Beer</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Haematology, Addenbrooke's Hospital</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author><author><name sortKey="Buck, Georgina" sort="Buck, Georgina" uniqKey="Buck G" first="Georgina" last="Buck">Georgina Buck</name><affiliation wicri:level="4"><inist:fA14 i1="04"><s1>Clinical Trial Service Unit, University of Oxford</s1><s2>Oxford</s2><s3>GBR</s3><sZ>4 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Wheatley, Keith" sort="Wheatley, Keith" uniqKey="Wheatley K" first="Keith" last="Wheatley">Keith Wheatley</name><affiliation wicri:level="4"><inist:fA14 i1="05"><s1>Cancer Research UK Clinical Trials Unit, University of Birmingham</s1><s2>Birmingham</s2><s3>GBR</s3><sZ>5 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region><settlement type="city">Birmingham</settlement></placeName><orgName type="university">Université de Birmingham</orgName></affiliation></author><author><name sortKey="Kiladjian, Jean Jacques" sort="Kiladjian, Jean Jacques" uniqKey="Kiladjian J" first="Jean-Jacques" last="Kiladjian">Jean-Jacques Kiladjian</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Assistance Publique des Hôpitaux de Paris Hopital Saint-Louis, Centre d'Investigations Cliniques</s1><s2>Paris</s2><s3>FRA</s3><sZ>6 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Forsyth, Cecily" sort="Forsyth, Cecily" uniqKey="Forsyth C" first="Cecily" last="Forsyth">Cecily Forsyth</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Gosford Hospital</s1><s2>Gosford</s2><s3>AUS</s3><sZ>7 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Gosford Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Harrison, Claire N" sort="Harrison, Claire N" uniqKey="Harrison C" first="Claire N." last="Harrison">Claire N. Harrison</name><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>St Thomas's Hospital</s1><s2>London</s2><s3>GBR</s3><sZ>8 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Green, Anthony R" sort="Green, Anthony R" uniqKey="Green A" first="Anthony R." last="Green">Anthony R. Green</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Haematology, Addenbrooke's Hospital</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Haematology, University of Cambridge</s1><s2>Cambridge</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author></analytic><series><title level="j" type="main">Blood</title><title level="j" type="abbreviated">Blood</title><idno type="ISSN">0006-4971</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Blood</title><title level="j" type="abbreviated">Blood</title><idno type="ISSN">0006-4971</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Blood cell count</term><term>Blood vessel</term><term>Cohort study</term><term>Complication</term><term>Essential thrombocythemia</term><term>Hematology</term><term>Prospective</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Hémogramme</term><term>Vaisseau sanguin</term><term>Complication</term><term>Prospective</term><term>Etude cohorte</term><term>Hématologie</term><term>Thrombocytémie essentielle</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Prospective</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Essential thrombocythemia, a myeloproliferative neoplasm, is associated with increased platelet count and risk of thrombosis or hemorrhage. Cytoreductive therapy aims to normalize platelet counts despite there being only a minimal association between platelet count and complication rates. Evidence is increasing for a correlation between WBC count and thrombosis, but prospective data are lacking. In the present study, we investigated the relationship between vascular complications and 21 887 longitudinal blood counts in a prospective, multicenter cohort of 776 essential thrombocythemia patients. After correction for confounding variables, no association was seen between blood counts at diagnosis and future complications. However, platelet count outside of the normal range during follow-up was associated with an immediate risk of major hemorrhage (P = .0005) but not thrombosis (P = .7). Elevated WBC count during follow-up was correlated with thrombosis (P = .05) and major hemorrhage (P=.01). These data imply that the aim of cytoreduction in essential thrombocythemia should be to keep the platelet count, and arguably the WBC count, within the normal range. This study is registered at the International Standard Randomized Controlled Trials Number Registry (www.isrctn.org) as number 72251782.</div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Grand Londres</li><li>Midlands de l'Ouest</li><li>Oxfordshire</li><li>Île-de-France</li></region><settlement><li>Birmingham</li><li>Cambridge</li><li>Londres</li><li>Oxford</li><li>Paris</li></settlement><orgName><li>Université d'Oxford</li><li>Université de Birmingham</li><li>Université de Cambridge</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Campbell, Peter J" sort="Campbell, Peter J" uniqKey="Campbell P" first="Peter J." last="Campbell">Peter J. Campbell</name></noRegion><name sortKey="Beer, Philip A" sort="Beer, Philip A" uniqKey="Beer P" first="Philip A." last="Beer">Philip A. Beer</name><name sortKey="Beer, Philip A" sort="Beer, Philip A" uniqKey="Beer P" first="Philip A." last="Beer">Philip A. Beer</name><name sortKey="Buck, Georgina" sort="Buck, Georgina" uniqKey="Buck G" first="Georgina" last="Buck">Georgina Buck</name><name sortKey="Campbell, Peter J" sort="Campbell, Peter J" uniqKey="Campbell P" first="Peter J." last="Campbell">Peter J. Campbell</name><name sortKey="Green, Anthony R" sort="Green, Anthony R" uniqKey="Green A" first="Anthony R." last="Green">Anthony R. Green</name><name sortKey="Green, Anthony R" sort="Green, Anthony R" uniqKey="Green A" first="Anthony R." last="Green">Anthony R. Green</name><name sortKey="Harrison, Claire N" sort="Harrison, Claire N" uniqKey="Harrison C" first="Claire N." last="Harrison">Claire N. Harrison</name><name sortKey="Maclean, Cathy" sort="Maclean, Cathy" uniqKey="Maclean C" first="Cathy" last="Maclean">Cathy Maclean</name><name sortKey="Maclean, Cathy" sort="Maclean, Cathy" uniqKey="Maclean C" first="Cathy" last="Maclean">Cathy Maclean</name><name sortKey="Wheatley, Keith" sort="Wheatley, Keith" uniqKey="Wheatley K" first="Keith" last="Wheatley">Keith Wheatley</name></country><country name="France"><region name="Île-de-France"><name sortKey="Kiladjian, Jean Jacques" sort="Kiladjian, Jean Jacques" uniqKey="Kiladjian J" first="Jean-Jacques" last="Kiladjian">Jean-Jacques Kiladjian</name></region></country><country name="Australie"><noRegion><name sortKey="Forsyth, Cecily" sort="Forsyth, Cecily" uniqKey="Forsyth C" first="Cecily" last="Forsyth">Cecily Forsyth</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005D51 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005D51 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:12-0349846
|texte= Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort
}}
| This area was generated with Dilib version V0.6.33. |  |